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Elton-MarshallTDriezenPFongGTCummingsKMPersoskieAWackowskiOet al

Tobacco and cannabis use patterns are also evolving, and many teens are combining the two products

We used 353 independent single-nucleotide polymorphisms associated with cigarette smoking initiation as instrumental variables at genome-wide significance threshold ( p 0.1), leaving 353 independent instrumental variables for smoking initiation