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Both the effect of smoking on microbiome in CF patients and the possible causal relationship between smoking-induced variations of microbiome, possibly through CTFR dysfunction, and the clinical manifestations of CF, could not be proved

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[92] identified the differentially expressed lncRNA in smoking and non-smoking patients with COPD through RNA sequencing and bioinformatics analysis and found that ninety-six lncRNA were identified in non-smoking patients, while forty-four lncRNA were identified in smoking patients with COPD

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