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In contrast, there was a significant, dose-dependent increase in peak plasma CBD, and in plasma CBD AUC, as CBD:THC ratio increased ( p 0.008, Fig

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Epidemiological data also suggest that electronic cigarette users appear to be younger, more educated, with higher income, and a slight and variable prevalence of men and white people.14 Data from the BRFSS also showed that electronic cigarette use is a common habit, especially among younger adults, current cigarette smokers and people with comorbid conditions.9,10 There is an alarming uptrend in the use of electronic cigarettes among US high school students, with a prevalence ranging from 10 to 13% in 2016.15 In the most recent annual National Youth Tobacco Survey, the Centers for Disease Control and Prevention found that the number of high school students using tobacco, including electronic cigarettes, increased by 38%, with most of the new smokers using electronic cigarettes

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