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However, little is known about cannabis and tobacco co-use in adolescents at risk for psychosis. Substance use patterns tobacco only, cannabis only, co-use, other substances and no substance use were assessed over a two-year period in 734 individuals at clinical high risk for psychosis and 278 healthy controls

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The Fourth Circuit's ruling will bind Maryland, Virginia, West Virginia, North Carolina, and South Carolina, and will likely shape how other circuits read the question