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This fact known as the gateway effect of e-cigarettes for nicotine dependence and cigarette smoking is of particular importance, as the extensive body of literature provides unequivocal evidence that tobacco use in the form of cigarette smoking is the leading preventable cause of premature death and the major causal factor for ischemic heart disease, stroke, lung cancer, COPD and numerous other tobacco-related diseases that affect almost every organ in the human body (4, 10)

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Recessed filter rods feature a hollow mouth-end cavity that helps cool and soften smoke before inhalation

Appendices Appendix 1: Methodology and survey weighting Methods This briefing reports the results of the ASH Smokefree GB surveys on the use of vapes among adults in Great Britain