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The opening comes following the announcement from the Public Health England Report which estimates e-cigarettes are 95% less harmful to health than a normal cigarette and the recently introduced regulation for the EC, TPD (Tobacco Product Directive) whereby products have to be compliant with the regulation by May 2017

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Although the survey of the respondents was concise, the possible involvement of human factors cannot be ruled out because some of the respondents used other tobacco products occasionally (e.g., at gatherings), which could affect oral changes