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In this sentence, le is a direct object pronoun meaning it

Less oxygen availability lowers the highly efficient aerobic energy production and destroys your stamina profoundly

In parallel, the smoking-induced CO binds with haemoglobin and myoglobin, reduces arterial O2 blood saturation, and compromises the efficiency of respiratory enzymes, resulting in dysfunction of the O2 production, transportation and delivery system, especially during exercise

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I saw this very white-faced boy in the corner with big lips, and I had never seen a white person with lips that big anyway, so I didnt know who he was or what race he was. The one thing she did realize was that he liked black women, liked to play around with them. Then she found out that he was the songwriter