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2025;45:e70006

Research has indicated that biomarkers linked to oxidative stress, such as urinary 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), nitrite (NO 2 ), nitrate (NO 3 ), and biopyrrin, are significantly increased in AD patients (2224)

SAS is used to treat chronic inflammation in joints (Ward et al., 2019), inflammatory bowel disease (Jeong et al., 2019), and various cutaneous diseases, including alopecia areata, lichen planus, and chronic idiopathic urticaria (Orden et al., 2014

784,785 Pre-stroke exercise intervention alleviates stroke-induced ferroptosis by reducing the production of LPO, upregulating GPX4 and SLC7A11, and downregulating ACSL4, thereby reducing the size of cerebral infarction and improving the neurological function of ischemic stroke rats

The extracellular-single-regulated kinases (ERK) is the most important subfamily of mitogen-activated protein kinases (MAPK) for cell proliferation (Yu et al., 2022)