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Collectively, our findings emphasize brain regions (e.g., vmPFC, insula, thalamus) and circuits (e.g., insula-thalamus) linked with chronic smoking, suggest neuroimaging paradigms warranting additional consideration among smokers (e.g., pain processing), and point to regions in need of further elucidation in addiction (e.g., cerebellum)

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Researcher Steve Lee, an associate professor of psychology at UCLA and lead author of the 2013 meta-analysis agrees: "I have little doubt that stimulant medication is being prescribed without careful diagnostic procedures and that's a significant problem." "But it's also the case that in some communities children, and probably some adults, who could respond therapeutically and safely are being underprescribed and not getting the treatment they need," he says.