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In one widely cited 2010 study published in the Proceedings of the National Academy of Sciences , researchers found that nicotine coating indoor surfaces reacts with ordinary airborne nitrous acid to generate fresh tobacco-related compounds hours after the cigarette is out, which is precisely why a room can smell smoky again the morning after you were sure you had cleared it

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For example, a randomized clinical study observed that the transition from tobacco cigarettes to e-cigarettes was associated with a rapid improvement in vascular health (endothelial function, arterial stiffness)