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Harmonized EU product rules and tightly administered national enforcement push manufacturers to standardize ingredients, labeling, and manufacturing controls, which strengthens expectations for traceability and risk governance from the outset

We used Twitter data because they are free and publicly available and because of the documented prevalence of health misinformation on Twitter.17 18 It is estimated that just over one in 5 Americans (22%) and 45% of social media users in the UK use Twitter.19 20 This study comprised US and UK participants as the contrasting policy approaches toward e-cigarette use across the two countries may mean that US and UK participants view harms associated with e-cigarettes differently

In the validation study in a sample of 387 adolescents, only 6 (1.5%) showed measurable cotinine concentrations

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