CA-Cy3 protac Additionally

Additionally

making it useful for both short- and long-term imaging applications

Solubility and physicochemical properties can be finely tuned through selection and combination of these groups

612 SMILES: OC(=O)C1=CC=C(C(=C1)C([O-])=O)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34

1038/nature13527

CA-Cy3 protac AdditionallyHaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA Cy3 is a HaloTag ligand with Cyanine3 dye. Cy3 (Cyanine 3, 550Ex 570Em) is known for