MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg HaloPROTACS: Use of Small Molecule

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

209 SMILES BrCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-5'-propargyl-OH Synonyms CAS Number 1216805-32-1 Related CAS Molecular Formula C16H12N2O5 Molecular Weight 312

Degrader building block for targeted protein degradation

42 SMILES Cl

MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg HaloPROTACS: Use of Small MoleculeMaP555 Alkyne is is a fluorogenic probe. MaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The