DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol bioorthogonality

bioorthogonality

475 SMILES BrCCOCCOCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Pomalidomide-PEG4-C2-Br Synonyms Pomalidomide-4'-PEG4-C2-Br CAS Number n/a Related CAS Molecular Formula C23H30BrN3O8 Molecular Weight 556

SNAP-tag is smaller than HaloTag (33 kDa)

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol bioorthogonalitySOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing