Thalidomide-5'-piperidine-C1-alcohol Size:25mg 9 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC)

9 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It binds to the VHL E3 ligase with an IC50 of 0

84 SMILES: [O-]S(=O)(=O)C1=CC=C(C=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCCN1C(=O)C=CC1=O

Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction

which allow for sensitive detection in various imaging and analytical techniques

Thalidomide-5'-piperidine-C1-alcohol Size:25mg 9 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide 5' piperidine C1 alcohol Synonyms CAS Number 2229717 49 9 Related CAS Molecular Formula C19H21N3O5 Molecular Weight 371. 393 SMILES OCC1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95%