DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name Thalidomide-5'-piperidine-acid Synonyms CAS

Product Name Thalidomide-5'-piperidine-acid Synonyms CAS Number 2467965-70-2 Related CAS Molecular Formula C19H19N3O6 Molecular Weight 385

S)-AHPC-CO-C3-NH2 HCl Synonyms CAS Number 2940858-65-9 Related CAS 2361119-88-0 (free base)

S6-04-S6-04

Datasheet          MSDS

374 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name Thalidomide-5'-piperidine-acid Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing