Fmoc-Val-Cit-PAB dsa Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C89H151N15O27 Molecular Weight 1863

676 SMILES CC(C)(C)OC(=O)NCCCCN1CCN(CCN2CCN(CCOCCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NRX-2663 is an enhancer of the interaction between beta-catenin and beta-TrCP

918 Purity (HPLC) >= 95% Solubility DMSO

362 SMILES OCCCCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB dsa Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CASFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7