CR8 Size:5mg NCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95%

NCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C4-OH Synonyms Thalidomide-4'-O-acetamido-C4-OH CAS Number n/a Related CAS Molecular Formula C19H21N3O7 Molecular Weight 403

46 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(O)=O)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

6 Purity (HPLC) >= 95% Physical Appearance Red solid Optical Properties Abs/Em Maxima: 553/580 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

86 Purity (HPLC) >= 95% Solubility DMSO

CR8 Size:5mg NCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95%(R) CR8 acts as a molecular glue degrader that depletes cyclin K. Product Name CR8 Synonyms CAS Number 294646 77 8 Related CAS Molecular Formula C25H30N6O Molecular Weight 430. 556 SMILES CC[C@H](CO)CC1=NC(NCC2=CC=C(C=C2)C2=CC=CC=N2)=C2N=CN(C(C)C)C2=N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory