Pomalidomide-5'-C5-OH Size:50mg SHP099 suppresses RAS–ERK signalling to

SHP099 suppresses RAS–ERK signalling to inhibit the proliferation of receptor-tyrosine-kinase-driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models

Product Name 2-[4-(2-aminoethyl)piperazin-1-yl]ethan-1-amine Synonyms Piperazine-1

Product Name thalidomide bromide Synonyms Thalidomide-4' bromide CAS Number 2093536-12-8 Related CAS Molecular Formula C14H10BrNO4 Molecular Weight 336

S)-AHPC-CO-PEG2-C2-acid Synonyms CAS Number 2172820-09-4 Related CAS Molecular Formula C30H42N4O8S Molecular Weight 618

419 SMILES OCCOCCOCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Pomalidomide-5'-C5-OH Size:50mg SHP099 suppresses RAS–ERK signalling toDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Pomalidomide 5' C5 OH Synonyms CAS Number 2736496 58 3 Related CAS Molecular Formula C18H21N3O5 Molecular Weight 359. 382 SMILES OCCCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room