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Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 1-dimethylethyl ester CAS Number 149554-09-6

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 1-dimethylethyl ester CAS Number 149554-09-6SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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Description

1-dimethylethyl ester CAS Number 149554-09-6 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

248 SMILES NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl 4-[2-(piperazin-1-yl)ethyl]piperazine-1-carboxylate Synonyms CAS Number 164332-19-8 Related CAS Molecular Formula C15H30N4O2 Molecular Weight 298

making the linkers highly adaptable for diverse ADC and related applications

Product Name Lenalidomide-CO-PEG2-Cl Synonyms Lenalidomide-4'-CO-PEG2-Cl CAS Number n/a Related CAS Molecular Formula C20H24ClN3O6 Molecular Weight 437

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 1-dimethylethyl ester CAS Number 149554-09-6SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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