Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand Mukhopadhyay

Name: Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand Mukhopadhyay
Brand: creatorsinfotech.com
SKU: 52157977915
Price: 445.00 USD
Availability: InStock
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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand MukhopadhyaySOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

SKU: 52157977915 · From creatorsinfotech.com

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Description

Mukhopadhyay

214 Purity (HPLC) >= 95% Solubility DMSO

and photostability

438 Purity (HPLC) >= 95% Solubility DMSO

The water soluble 5(6)-FAM PEG3 azide has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal azide group

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