Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan fluorescent Product Name 1-bromo-4-(methoxy-d3)benzene Synonyms 1-bromo-4-(²H3)methoxybenzene

Product Name 1-bromo-4-(methoxy-d3)benzene Synonyms 1-bromo-4-(²H3)methoxybenzene CAS Number 100835-59-4 Related CAS Molecular Formula C7H7BrO Molecular Weight 190

35 Purity (HPLC) >= 95% Solubility DMSO

301 SMILES OCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The azide group (N3) reacts with terminal alkynes to produce a stable triazole

Product Name Pomalidomide-PEG5-OH Synonyms Pomalidomide-4'-PEG5-OH CAS Number 2140807-34-5 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan fluorescent Product Name 1-bromo-4-(methoxy-d3)benzene Synonyms 1-bromo-4-(²H3)methoxybenzeneSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by