Azide-Dap(m-PEG4)-Val-Cit-PAB 5' as the acetylation masks the

as the acetylation masks the hydroxyl groups critical for fluorescein’s fluorescence

87 SMILES Cl

S)-AHPC-acetamido-O-PEG3-propargyl Synonyms CAS Number 2098799-81-4 Related CAS Molecular Formula C33H46N4O8S Molecular Weight 658

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

Product Name Fmoc-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H77N7O19 Molecular Weight 1176

Azide-Dap(m-PEG4)-Val-Cit-PAB 5' as the acetylation masks theSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine