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Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan This ADC building block is

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan This ADC building block isSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

SKU: 95285713213 · From creatorsinfotech.com

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Description

This ADC building block is widely used in the synthesis of antibody-drug conjugates for cancer research

291 SMILES BrCCCCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

selective and orally bioavailable small-molecule SHP2 inhibitor

328 SMILES OC(=O)CCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

182 SMILES [2H]C([2H])([2H])OC1=CC=C(C)C(=C1)N(=O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan This ADC building block isSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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