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Therefore, macrophage ferroptosis may be considered to be involved in the progression of AS (97) and could serve as a potential target for intervention with AS progression

3335 Both X-ray crystal and cryoEM structures of 2-OG bound dodecameric GS revealed that 2-OG filled a critical pocket in between monomers within the hexamer and enforce a mechanism whereby glutamine synthesis only occurs under carbon replete conditions

Kojer et al., The redox couples present in organelles of the exocytic pathway display redox poises similar to the extracellular space

-HB affects signaling factors, including GPCRs in the cytoplasm, histones in the nucleus, and HDACs, hnRNP A1, and p53 in the cytoplasm

The cAMP response element-binding (CREB) protein mediates histone deacetylase inhibitors, suggesting that the cAMP pathway may alter histone modifications following sleep deprivation