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Compared to erythrocytes cultured in Ringer solution alone (T 1h =0.1% and T 48h =2.4%

or blood flow at 1hrPrEX, 90%, 100%, or 110%

Certain substances may share the same cytochrome P450 specificity, thus competitively block their biotransformation activity and lead to accumulation of drugs metabolized by the enzyme

This test particularly benefits individuals with chronic health conditions, digestive disorders affecting absorption, athletes with increased nutrient demands, and those following restrictive diets

Median (interquartile range) treatment duration during the OLE phase was 35.1 (25.137.0) and 35.3 (33.637.3) weeks for the FAZFAZ and PBOFAZ cohorts, respectively