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For OCR, 1.5 mol/L oligomycin (ATP synthase inhibitor), 2 mol/L FCCP (mitochondrial uncoupler) and 0.5 mol/L rotenone/antimycin A (Complex I/III inhibitors) were sequentially added to the culture plate and maximal respiration and non-mitochondrial respiration values derived from OCR kinetics were recorded

Together, our findings reveal how modest sequence divergence within a conserved architectural motif can drive functional specialization of transcriptional coactivators, providing insight into the evolution of transcriptional regulation and its adaptation to pathogenic lifestyles

Yang M, et al

Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes

In addition, flavonoids are involved in a variety of plant life activities, such as auxin transport, root and stem development, and regulation of plant response to external stress