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Nitrogen is a component of proteins, amino acids, nucleotides, and nucleic acids (Koohkan and Maftoun, 2016)

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In addition, we selected a ligand-binding configuration that adopted a catalytically active pose, which placed the proton-donating C3 position of NADP near the nitrogen-adjacent tertiary carbon of R -THIQ

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Individual pools and combinations were evaluated for l-carnitineTMA activity using a fractional factorial design (Figure 6B)