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The identification of reliable validated biomarkers could facilitate earlier and more accurate diagnosis and drive the development of targeted pharmacological therapies that might address the underlying pathophysiology of these diseases

Multi-modal, longitudinal imaging of neurotransmitters, AD pathology and associated molecular mechanisms in LLD (oxidative stress, mitochondrial dysfunction) are critical to understanding the vulnerability of these monoaminergic nuclei and the interrelationships in critical cortical and limbic regions [343,344,345]

There are multiple potential mechanisms by which PPI use can induce IBD

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Alin Laurentiu Tatu, Dunarea de Jos University, Romania