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It was found that ASRS scores were increased in patients with SLE compared with control subjects, and that this score was reduced in SLE patients treated with NAC [21]

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Key benefits and findings include: Antioxidant Action: PLE reduces oxidative stress, a critical factor in melasma, by neutralizing free radicals and minimizing UV-induced inflammation

Kaempferol regulated melanocytes dendritic growth and melanosome quantity, maturation, and transport via P38/ERK MAPK and PI3K/AKT signalling pathways [220]

(2003) was carried out in a broader region of southern Germany, which included the Arnsberg region, by the same team of investigators but covered the calendar period 1992-2000 and a different set of cases and controls