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Oxidative injury to lysosomal membrane proteins (e.g., LAMP2) blocks autophagic flux and causes p62 accumulation (Wang X

That translates to roughly $60 to $150 per month, depending on the source and dosage

Mild Dizziness: A sensation of lightheadedness can occur, particularly during dose adjustments

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Taken together, this also demonstrates that Fc-engineered human IgG variants with altered binding to FcRn behave differently in human and murine model systems, which highlights the importance of accounting for cross-species differences when studying Ab-based therapeutics and FcRn biology [101,102,103]