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Whether it is from the heightened risk of disease, a higher chance of crashing or just losing money on the trade in, driving and smoking are two activities that should never be mixed

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Nevertheless, complement activation in the pathogenesis of cardiovascular disease is well described, from the earliest signs of endothelial dysfunction, followed by progression to the formation of atherosclerotic plaques and vascular thrombus, with accompanied proinflammatory and procoagulant changes [63, 64]