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We provide evidence that this targeting concept can be used to antagonize NMDA receptors specifically in GLP-1-receptor-positive neurons to reverse obesity and correct symptoms of cardiometabolic diseases in preclinical obesity models

Recall that Shc ultimately activates the MAPK pathway, while PLC has more metabolic effects including GLUT4 translocation

It was observed that the proliferation of MCF-7, Caco-2, and HeLa cells was significantly inhibited by water-soluble extracts of camel milk rather than bovine milk fermented by strains like L

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They can act as scaffolds, decoys, or guides to interact with proteins and other regulatory molecules, ultimately affecting the expression of pain-related genes [203]