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Current treatment modalities and limitations Pharmacological treatment remains the primary current approach to managing PD, with levodopa considered the gold standard for alleviating motor symptoms 51

D.IkedaM.IdeT.TadokoroT.FurusawaS.AbeK.et al (2022)

The effect became even more pronounced as the supplementation duration extends to the 18th week (Lee M.-C

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Emerging platforms, such as gold nanoparticles or bioreducible lipid nanoparticles, further enhance this synergy by facilitating endosomal escape and intracellular release of Cas9-sgRNA ribonucleoproteins (RNPs) [310]