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doi: 10.7150/jca.71894 132 ToSKYTangMKSTongYZhangJChanKKLIpPPCet al

Abstract The ability to generate and regulate energy, maintain metabolic flux, and preserve redox homeostasis is the basis of all cellular processes in both healthy and diseased tissues

Glutathione increases your overall antioxidant defense and blocks the inflammatory cytokines

Free radicals can damage cells and DNA if left unchecked, resulting in issues such as: Increased signs of aging (such as wrinkled or dry skin) Headaches Low energy levels Increased risk of illness Lack of mental clarity Joint pain Fatigue Antioxidants, such as glutathione, rid the body of free radicals before they can do too much harm

The ALOX family can mediate PUFAs peroxidation to generate AA/AdA-PE-OOHs, thereby triggering ferroptosis (Lei et al., 2019)