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Department of Cellular and Molecular Medicine, University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA

LC3-II and Beclin-1 are key molecules in the autophagy pathway, induction of HO-1 activates the autophagy pathway by increasing the expression of LC3-II and Beclin-1, thereby removing harmful substances from cardiomyocytes [108]

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Vehicle-dosed GAN DIO-MASH mice remaining on the GAN diet served as controls (n=13)

The standalone BPC-157 protocol is a focused, lower-cost entry point for patients who want to explore peptide therapy for a specific concern, particularly gut health, mild joint issues, or general recovery support