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[DOI] [PubMed] [Google Scholar] Jiang R, Hu FB, Giovannucci EL, Rimm EB, Stampfer MJ, Spiegelman D, Rosner BA, Willett WC

Lysine acetyltransferase 2A (KAT2A), also known as general control non-depressible 5 (GCN5) and belonging to the GCN5-related N-acetyltransferase (GNAT) subfamily of HAT, functions as the lactyltransferase responsible for H3K18la, implying the role of GCN5 as a writer for histone Kla

The FDA has released a series of documents since 2017 detailing how RWE may be used in submissions for medical devices, drugs, and biologics, including its 2018 Framework for Real-World Evidence and more recent guidance on data standards and the evaluation of electronic health record and claims data

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Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, Hfner M, Schmiegel WH