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Differential genes in PD oligodendrocytes and astrocytes To investigate the potential pro-inflammatory interaction between oligodendrocytes and astrocytes in PD based on the FGF signaling pathway, we further characterized the differentially expressed genes in oligodendrocytes and astrocytes to assess their specific functional roles in PD (Figs

Studies have shown that inhibiting the HMGB1-TLR4 axis significantly reduces hepatic cell pyroptosis and improves liver function in HIRI mouse models (182, 190)

doi: 10.1021/jm049568z 132 KirshnerJRHeSBalasubramanyamVKeprosJYangC-YZhangMet al

Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity