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The combined use of MS-HRM and dMS-HRM allowed for the assessment of the extent and complexity of heterogeneous methylation revealing visible patterns

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations E-GPx: extracellular glutathione peroxidase C-GPx: cellular glutathione peroxidase GPx-GI: gastrointestinal glutathione peroxidase GPx: seleniumdependent glutathione peroxidase IBD: inflammatory bowel disease DSS: dextran sodium sulfate GI: gastrointestinal t-BuOOH: tert-butyl hydroperoxide GSH: glutathione SSC: saline-sodium citrate GAPD: glyceraldehyde-3 phosphate dehydrogenase References Parks DA, Bulkley GB, Granger DN 1983 Role of oxygen-derived free radicals in digestive tract diseases

Patients with moderate glutathione deficiency experience symptoms of hemolytic anemia and metabolic acidosis, which is characterized by increased acid production in the tissues and blood

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The blood glucose level was 2.42 mmol/L, accompanied by an inappropriately high serum insulin level of 117.8 IU/ml and a C-peptide level of 8.87 ng/ml