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doi: 10.9758/cpn.2017.15.1.1

As a result, the production of mature IL-1 was decreased following activation of NLRP3 by nigericin or ATP, with no effect on pyroptosis

10.1126/science.aap7847 Science Summary Keywords malaria, Plasmodium berghei , glutathione S-transferase, drug target, structure-based screening, shape similarity screening, antimalarial drug discovery, predicted pharmacokinetic and toxicity parameters Citation Coln-Lorenzo EE, Coln-Lpez DD, Vega-Rodrguez J, Dupin A, Fidock DA, Baerga-Ortiz A, Ortiz JG, Bosch J and Serrano AE (2020) Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

"We know that's a lot of inappropriate care that happens in Canada," said study co-author Dr