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The hypersecretion of cortisol (corticosterone in rodents) causes neuronal damage and structural disturbances in the hippocampus, resulting in depression symptoms ( Two third of depression patients are female, largely due to the frequent fluctuation of sex hormones in addition to environmental and genetic factors ( Stress is known to increase cortisol level and subsequently decrease the release of thyroid stimulating hormone (TSH) ( 2.4 Neurogenesis and neuroplasticity hypothesis Depression is an emotional disease and may show signs at the cell and organ levels

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Omega-3 fatty acids and antioxidants in neurological and psychiatric diseases: an overview

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