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The 2022 Dimet-Wiley paper in Scientific Reports characterised NNMT inhibition combined with reduced-calorie diet in diet-induced-obesity mouse model systems (PMID 35013352)

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When delivered via injection, L-Carnitine bypasses the digestive system and is rapidly absorbed into the bloodstream, accelerating this fat-burning process more efficiently than oral supplements

NNMT Inhibition At the core of 5-Amino-1MQs effects is its ability to inhibit nicotinamide N-methyltransferase (NNMT) , an enzyme found in multiple tissues including fat cells, liver, and muscle