l carnitine downsides Potential Adverse Effects of L-Carnitine Acetyl-L-Carnitine: Benefits and Side Effects

Long-term toxicological studies also suggest that AS-IV has low toxicity

Nat Med 24:15791589 Rothstein JD, Caroline Warlick ANC (2023) Highly variable molecular signatures of TDP-43 loss of function are associated with nuclear pore complex injury in a population study of sporadic ALS patient iPSNs

Grin2a Hypofunction Disrupts Hippocampal Network Oscillations and E/I Balance Contributing to Cognitive Deficits

Furthermore, although LOLA initially lowers blood ammonia levels, even in end-stage liver disease, its effects appear to be temporary as a rebound hyperammonemia is sometimes observed on cessation of the drug [72]

None of them comes anywhere close to having reasonable evidence that they actually work in humans, but if youre a that empty glass has a few drops of water in it kind of guy, most of them also havent been shown not to work