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TLR4 activation has been directly implicated in PD pathogenesis, as demonstrated by elevated TLR4 expression in both human patients and murine models with PD, driving microglial activation and dopaminergic neuron loss (51)

Cold peptide solution causes more discomfort at the injection site and can lead to increased local reactions

J., Datta S

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Effect of insulin-like growth factor-I treatment on serum androgens and testicular and penile size in males with Laron syndrome (primary growth hormone resistance)