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Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R

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In cancer cells, high concentration of NO can damage various macromolecules such as nucleic acids and proteins and finally trigger apoptosis

GC67918 MPO-IN-1 GC36650 MPO-IN-28 MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM

This method is based on the color reaction between allyl thiourea and potassium ferricyanide solution in dilute acetic acid which measures the optical density of the color complex at 600 nm and it works in the range of 2.5 to 7.5 picogram of AITC per milliliter of the color solution