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Pyroptosis, in contrast, involves caspase-1 activation by inflammasomes like NLRP3, leading to cytokine release and membrane permeability increase [150, 151]

By regulating cellular pathways and gene expression patterns, the copper peptide complex facilitates the repair of damaged proteins and promotes the generation of new, healthy skin cells

Migrasomes have been found to promote fibrosis [160], suggesting that they also have an active role in this process

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In some models, this increase was observed as early as day three and reached up to sevenfold compared to baseline