l-carnitine side effects fishy odor tmao heart disease Comparison of short-term and long-term of peroral intake: clinical implications of elevated levels in cardiovascular complications Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis:

Author: Gianpiero Pescarmona Date: 12/06/2013 Carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.In living cells, it is required for the transport of fatty acids from the cytosol into the mitochondria during the breakdown of lipids (fats) for the generation of metabolic energy

Autophagy 8 (1), 122123

At the same time, it downregulates the expression of multiple drug efflux pumps in tumor cells, thereby reversing multidrug resistance (MDR) and increasing the intracellular accumulation and cytotoxicity of chemotherapeutic agents such as cisplatin, paclitaxel, and 5-FU (Ghosh et al., 2022)

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