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The transcription factor NF-B/p65, the expression of cellular inflammatory factors (IL-1, IL-6, IL-11, and TNF-), is regulated by Akana

Oxygen saturation (SatO2), measured with a pulse oximeter (V24C, Agilent Technologies, Bblingen, Germany), varied between 70% and 83%, and did not increase after application of a non-rebreathing mask with 15 L/min oxygen

290,291,292 Accumulating macrophages release cytokines and chemokines, including IL-1, IL-6, chemokine ligand 2 (CCL2), and TNF-, intensifying the inflammatory environment and aggravating nerve damage