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Description

Some anticoagulants, such as warfarin, act by reducing the vitamin K epoxide reductase-catalysed recycling of oxidised vitamin K, thereby limiting the carboxylation of the precursors of factors II (prothrombin), VII, IX and X to their mature forms (Fig

doi: 10.1038/s41467-018-05844-8 46 DentK

MICROSOMAL MIXED FUNCTION OXIDASE SYSTEM & PHASE I REACTIONS Many drug-metabolizing enzymes are located in the lipophilic endoplasmic reticulum membranes of the liver and other tissues