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Experiments using macrophage-like (leukemia RAW 264.7) cells confirmed the very good ROS scavenging efficiency of this Se-containing nanozyme

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To overcome these research bottlenecks, future studies should conduct more systematic in vivo experiments to simulate the complex physiological microenvironment, while designing more rigorous experimental protocols to elucidate the precise mechanisms by which TCM target the Wnt/-catenin signaling pathway in CRC treatment

*Correspondence: Haider Raza, [email protected] This article was submitted to Metabolic Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers